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Principles of Neurobiology

Liqun Luo

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Chapter   
  • Flashcards (13)

  • Movies (42)

    Viewing 1 - 10 of 42 results
    • 2.1 Escape Behavior

      [video/quicktime, 3.54 MB]

      Chapter Name:
      Chapter 2: Signaling within Neurons
      Description:

      Zebrafish larvae respond quickly to external stimuli, tested experimentally here with a water pulse from a tube against its tail. The zebrafish completely changes its direction within a few milliseconds of stimulation.

      ...
    • 2.2 Organelle Movement on Microtubules

      [video/quicktime, 5.12 MB]

      Chapter Name:
      Chapter 2: Signaling within Neurons
      Description:

      In this experiment a cell homogenate containing many different organelles is added to microtubules. Motor proteins are normally attached to the organelles. When ATP is added as a fuel for the motor proteins, some organelles

      ...
    • 2.3 Kinesin

      [video/quicktime, 6.61 MB]

      Chapter Name:
      Chapter 2: Signaling within Neurons
      Description:

      The motor protein kinesin is a dimer with two identical motor heads. Each head consists of a catalytic core and a neck linker. In the cell, kinesins pull organelles along microtubule tracks. The organelle attaches to the other

      ...
    • 2.4 Transport by Carrier Proteins

      [video/quicktime, 10.42 MB]

      Chapter Name:
      Chapter 2: Signaling within Neurons
      Description:

      Cells possess a variety of membrane proteins to ferry solutes across the membrane. One type of transporter, called a uniport, carries only one type of solute, selectively bringing it from one side of the membrane to the other.

      ...
    • 2.5 Na+-K+ATPase

      [video/quicktime, 10.44 MB]

      Chapter Name:
      Chapter 2: Signaling within Neurons
      Description:

      Animal cells store energy in the form of ion gradients across the cell membrane. In the cytosol, the sodium ion concentration is kept low relative to the extracellular fluid, and conversely the potassium ion concentration in

      ...
    • 2.6 Electrical Properties of Neurons

      [video/quicktime, 6.44 MB]

      Chapter Name:
      Chapter 2: Signaling within Neurons
      Description:

      In this idealized experiment, a cartoon neuronal fiber in extracellular fluid is used to demonstrate the electrical properties of neurons. A stimulating electrode is inserted into the membrane to inject current and a second,

      ...
    • 2.7 Action Potentials

      [video/quicktime, 7.23 MB]

      Chapter Name:
      Chapter 2: Signaling within Neurons
      Description:

      The fundamental task of a nerve cell is to receive, integrate, conduct, and transmit signals. Many neurons propagate signals along axons in the form of action potentials. Action potentials are able to travel great distances

      ...
    • 2.8 Potassium Channel Structure

      [video/quicktime, 6.10 MB]

      Chapter Name:
      Chapter 2: Signaling within Neurons
      Description:

      The bacterial potassium channel is a multipass transmembrane protein in the plasma membrane. It is built from four identical subunits that are arranged symmetrically. A pore in the center of the protein allows selective passage

      ...
    • 3.1 Synaptic Vesicle

      [video/quicktime, 7.16 MB]

      Chapter Name:
      Chapter 3: Signaling across Synapses
      Description:

      This model represents a cutaway view of a synaptic vesicle, with the membrane lipids and proteins drawn to scale. Each synaptic vesicle membrane contains approximately 7000 phospholipid molecules and 5700 cholesterol molecules.

      ...
    • 3.2 Synaptic Transmission

      [video/quicktime, 5.53 MB]

      Chapter Name:
      Chapter 3: Signaling across Synapses
      Description:

      Neurons transmit chemical signals across synapses, like the ones shown in this electron micrograph. We can identify the dendrite of the receiving, or postsynaptic cell, as well as two presynaptic nerve terminals loaded with

      ...
    Viewing 1 - 10 of 42 results
  • Other Resources (7)

    Viewing 1 - 7 of 7 results
    • Journal Club for Chapter 2

      [application/pdf, 467.16 kB]

      Chapter Name:
      Chapter 2: Signaling within Neurons
      Description:
      This PDF document includes background information, a reading guide, and questions and answers on the paper: Hodgkin AL & Huxley AF (1952) Currents carried by sodium and potassium ions through the membrane of the giant axon of ...
    • Journal Club for Chapter 3

      [application/pdf, 154.67 kB]

      Chapter Name:
      Chapter 3: Signaling across Synapses
      Description:
      This PDF document includes background information, a reading guide, and questions and answers on the paper: Magee JC & Cook EP (2000) Somatic EPSP amplitude is independent of synapse location in hippocampal pyramidal neurons. ...
    • Journal Club for Chapter 4

      [application/pdf, 132.01 kB]

      Chapter Name:
      Chapter 4: Vision
      Description:
      This PDF document includes background information, a reading guide, and questions and answers on the paper: Hubel DH & Wiesel TN (1962) Receptive fields, binocular interaction and functional architecture in the cat’s visual ...
    • Journal Club for Chapter 6

      [application/pdf, 397.41 kB]

      Chapter Name:
      Chapter 6: Olfaction, Taste, Audition, and Somatosensation
      Description:
      This PDF document includes background information, a reading guide, and questions and answers on the paper: Bhandawat V, Olsen SR, Gouwens NW, et al. (2007) Sensory processing in the Drosophila antennal lobe increases ...
    • Journal Club for Chapter 7

      [application/pdf, 233.04 kB]

      Chapter Name:
      Chapter 7: Wiring of the Nervous System
      Description:
      This PDF document includes background information, a reading guide, and questions and answers on the paper: Joo WJ, Sweeney LB, Liang L et al. (2013) Linking cell fate, trajectory choice, and target selection: genetic analysis of ...
    • Journal Club for Chapter 8

      [application/pdf, 487.73 kB]

      Chapter Name:
      Chapter 8: Motor and Regulatory Systems
      Description:
      This PDF document includes background information, a reading guide, and questions and answers on the paper: Atasoy D, Betley JN, Su HH et al. (2012) Deconstruction of a neural circuit for hunger. Nature 488:172–177.
    • Journal Club for Chapter 10

      [application/pdf, 220.35 kB]

      Chapter Name:
      Chapter 10: Memory, Learning, and Synaptic Plasticity
      Description:
      This PDF document includes background information, a reading guide, and questions and answers on the paper: Frey U & Morris RGM (1997) Synaptic tagging and long-term potentiation. Nature 385:533–536.
    Viewing 1 - 7 of 7 results