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Mass Spectrometry in Metabolomics

Mike Burrell
Publication Date:
July 31, 2008
Content Details:
350 pages

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  • About the Book

    Book Summary

    Each chapter of Mass Spectrometry in Matabolomics is written by an expert and contains background information, theory, pitfalls, benefits and practical applications. Data processing is emphasized in all relevant chapters and there are separate chapters on statistical analysis and how to fit data to metabolic pathways and gene expression. Both plants and animals are covered, paying particular attention to metabolomics in drug discovery.

  • Contents

    1. Introduction  2. Mass Spectrometry Soft Ionisation Techniques  3. MALDI  4. Imaging  5. Extraction Sample Handling  6. Metabolic Profiling of Plant Tissues by Electrospray Mass Spectrometry  7. Metabolite Mapping in Plants by GC/MS and LC/MS  8. Metabolic Profiling of Animal Tissues by Mass Spectrometry  9. Drug Metabolism in Animal tissues by Mass Spectrometry  10. Mapping Drugs and their Metabolites in Animal Tissues  11. Statistical Analysis of Data  12. How to Make Sense of the Data