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Case Studies in Immunology

A Clinical Companion

Raif Geha, Fred Rosen
Publication Date:
June 21, 2007
Content Details:
356 pages | 238 illustrations

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  • About the Book

    Book Summary

    Case Studies in Immunology, Fifth Edition cites major topics of immunology as the background to a selection of real clinical cases that serve to reinforce and extend the basic science. This new edition vividly illustrates the importance of an understanding of immunology in diagnosis and therapy. As well as being a valuable review aid, Case Studies in Immunology introduces in a clinical setting the major common disorders of immunity, including hypersensitivity types I-IV and autoimmune disorders such as lupus and multiple sclerosis. It also describes and explains the consequences of some of the most important immune deficiencies. Each case history is preceded by basic scientific facts essential to understanding the immunology behind the disease or disorder. An end-of-case summary, questions, and discussion points finish each case. Case Studies in Immunology can be used as a stand-alone book, or as a clinical companion alongside Janeway's Immunobiology, Seventh Edition (ISBN 0-8153-4123-9) and The Immune System, Third Edition (ISBN 0-8153-4146-8).

  • Contents

    1.Congenital Asplenia
    2. Chronic Granulomatous Disease
    3. Leukocyte Adhesion Deficiency
    4. Hereditary Angioneurotic Edema
    5. Factor I Deficiency
    6. Deficiency of the C8 Complement Component
    7. Hereditary Periodic Fever Syndromes
    8. Interleukin Receptor-associated Kinase Deficiency
    9. X-linked Hypohydrotic Ectodermal Dysplasia and Immunodeficiency
    10. X-linked Agammaglobulinemia
    11. X-linked Hyper IgM Syndrome
    12. Activation-induced Cytidine Deaminase (AID) Deficiency
    13. Common Variable Immunodeficiency
    14. X-linked Severe Combined Immunodeficiency
    15. Adenosine Deaminase Deficiency
    16. Omenn Syndrome
    17. MHC Class I Deficiency
    18. MHC Class II Deficiency
    19. Multiple Myeloma
    20. T-Cell Lymphoma
    21. Interferon-Receptor Deficiency
    22. Wiskott-Aldrich Syndrome
    23. X-linked Lymphoproliferative Syndrome
    24. Autoimmune Lymphoproliferative Syndrome (ALPS)
    25. Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked Disease
    26. Toxic Shock Syndrome
    27. Acute Infectious Mononucleosis
    28. Mixed Essential Cryoglobulinemia
    29. Rheumatic Fever
    30. Lepromatous Leprosy
    31. Acquired Immune Deficiency Syndrome (AIDS)
    32. Acute Systemic Anaphylaxis
    33. Allergic Asthma
    34. Atopic Dermatitis
    35. Drug-Induced Serum Sickness
    36. Celiac Disease
    37. Contact Sensitivity to Poison Ivy
    38. Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy (APECED)
    39. Autoimmune Hemolytic Anemia
    40. Myasthenia Gravis
    41. Pemphigus Vulgaris
    42. Rheumatoid Arthritis
    43. Systemic Lupus Erythematosus
    44. Multiple Sclerosis
    45. Hemolytic Disease of the Newborn
    46. A Kidney Graft for Complications of Autoimmune Insulin-Dependent Diabetes Mellitus
    47.Graft-Versus-Host Disease

  • Instructor Resources

    Instructor Resources

    The Art of Case Studies in Immunology, Fifth Edition
    Artwork available in JPEG and PowerPoint formats.

  • Student Resources

    Student Resources

    Case Studies in Immunology, Fifth Edition, can be used as a clinical companion alongside The Immune System, Third Edition. The Correlation Guide matches the relevant sections of each text so they can more easily be used in tandem.

  • E-book


    Case Studies in Immunology, Fifth Edition is now available in the US and Canada as a downloadable e-book from VitalSource.

    VitalBook technology enables students to:
    • Search the text
    • Add highlights and notes, and share them
    • Download to multiple devices, including iPads

    The various e-book options for Case Studies in Immunology, Fifth Edition enable students to save significantly over the printed version.
    • eBook purchase: $41.00 (30% off list price)
    • 1 year e-rental: $35.00 (40% off list price)
    • 180 day e-rental: $30.00 (50% off list price)
    • Individual chapters: $5.00 each

    To purchase or rent the e-book at the VitalSource store go to:

    E-chapter Purchase
    Individual case studies from Case Studies in Immunology, Fifth Edition are available for purchase electronically. Individual cases are $5 apiece in North America and £3.50 in the rest of the world. The complete eBook is $53 in North America and £33 in the rest of the world

    To purchase, please visit and type in the 13 digit ISBN from the list below.
    Complete eBook  978-0-203-85686-4
    978-0-203-85330-6 A Kidney Graft for Complications of Autoimmune Insulin-Dependent Diabetes Mellitus
    978-0-203-85353-5 Activation-induced Cytidine Deaminase (AID) Deficiency
    978-0-203-85372-6 Acquired Immune Deficiency Syndrome (AIDS)
    978-0-203-85368-9 Acute Infectious Mononucleosis  
    978-0-203-85332-0 Acute Systemic Anaphylaxis
    978-0-203-85356-6 Adenosine Deaminase Deficiency
    978-0-203-85334-4 Atopic Dermatitis
    978-0-203-85339-9 Autoimmune Hemolytic Anemia  
    978-0-203-85365-8 Autoimmune Lymphoproliferative Syndrome (ALPS)
    978-0-203-85338-2 Autoimmune Polyendocrinopathy-Candidiasis
    Ectodermal Dystrophy
    978-0-203-85336-8 Celiac Disease
    978-0-203-85343-6 Chronic Granulomatous Disease
    978-0-203-85354-2 Common Variable Immunodeficiency  
    978-0-203-85342-9 Congenital Asplenia
    978-0-203-85337-5 Contact Sensitivity to Poison Ivy
    978-0-203-85347-4 Deficiency of the C8 Complement Component
    978-0-203-85335-1 Drug-Indeuced Serum Sickness 
    978-0-203-85346-7 Factor I Deficiency
    978-0-203-85331-3 Graft-Versus-Host Disease
    978-0-203-85329-0 Hemolytic Disease of the Newborn  
    978-0-203-85345-0 Hereditary Angioneurotic Edema   
    978-0-203-85348-1 Hereditary Periodic Fever Syndromes
    978-0-203-85366-5 Immune Dysregulation,
    Polyendocrinopathy,Enteropathy X-linked Disease
    978-0-203-85349-8 Interleukin 1 Receptor-associated Kinase 4 Deficiency 
    978-0-203-85362-7 Interferon-y Receptor Deficiency
    978-0-203-85371-9 Lepromatous Leprosy  
    978-0-203-85344-3 Leukocyte Adhesion Deficiency 
    978-0-203-85357-3 Omenn Syndrome
    978-0-203-85369-6 Mixed Essential Cryoglobulinemia  
    978-0-203-85358-0 MHC Class I Deficiency  
    978-0-203-85359-7 MHC Class II Deficiency  
    978-0-203-85360-3 Multiple Myeloma
    978-0-203-85328-3 Multiple Sclerosis   
    978-0-203-85341-2 Pemphigus Vulgaris  
    978-0-203-85326-9 Rheumatoid Arthritis
    978-0-203-85370-2 Rheumatic Fever  
    978-0-203-85327-6 Systemic Lupus Erythematosus
    978-0-203-85361-0 T-Cell Lymphoma   
    978-0-203-85367-2 Toxic Shock Syndrome 
    978-0-203-85363-4 Wiskott-Lymphoproliferative Syndrome  
    978-0-203-74241-1 X-linked Agammaglobulinemia  
    978-0-203-85350-4 X-linked Hypohydrotic Ectodermal 
    Dysplasia and Immunodeficiency
    978-0-203-85352-8 X-linked Hyper IgM Syndrome
    978-0-203-85364-1 X-linked Lymphoproliferative Syndrome  
    978-0-203-85355-9 X-linked Severe Combined Immunodeficiency

  • Downloads

    Samples & Downloads

    Click on any of the links below to download a printable PDF of a sample chapter.

    Case 12: Activation-induced Cytidine Deaminase (AID) Deficiency