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Janeway's Immunobiology

Kenneth Murphy, Casey Weaver
Publication Date:
March 15, 2017
Content Details:
904 pages | 621 illustrations

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List Price:   $285.00

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  • About the Book

    Book Summary

    Janeway’s Immunobiology is a textbook for students studying immunology at the undergraduate, graduate, and medical school levels. As an introductory text, students will appreciate the book’s clear writing and informative illustrations, while advanced students and working immunologists will value its comprehensive scope and depth. Janeway’s Immunobiology presents immunology from a consistent point of view throughout—that of the host’s interaction with an environment full of microbes and pathogens.

    The Ninth Edition has been thoroughly revised bringing the content up-to-date with significant developments in the field, especially on the topic of innate immunity, and improving the presentation of topics across chapters for better continuity.


      New in the Ninth Edition:

        • Now organized around the concept of modular immune responses, combining innate and adaptive immunity into effector modules and explaining the integration of the innate and adaptive immune response.
        • Updated with the latest developments on innate lymphoid cells and innate sensing mechanisms, including cycling GMP-SMP synthase (cGAS) and activation of the STING pathway.
        • Incorporates the new mechanisms of class switch recombination involving RNA guides for AID.
        • Includes an expanded, updated coverage of CD4 T cell subsets, including an in-depth handling of follicular helper T cells and their role in B cell class switching and affinity maturation.
        • Improved coverage of chemokine networks and their role in coordinating immunity.
        • Includes new content on cytoskeletal reorganization and integrin activation in antigen receptor signaling and expanded coverage on Akt and mTOR signaling.
        • Revised and updated sections on mechanisms of immune evasion by pathogens and HIV/AIDS.
        • Updated and more detailed consideration of mechanisms of immunemediated disease.
        • Expanded coverage of cancer immunotherapy, including chimeric antigen receptor T cell (CAR T cell) therapy.
        • Comprehensive update to Appendix I: The Immunologist’s Toolbox, with the addition of many new techniques, including mass spectrometry, in vivo administration of antibodies, RNAi, and the CRISPR/Cas9 system.
        • Illustration program has been thoroughly updated with over 100 new figures and improved with newer and better images of protein structures and micrographs.
        • Completely updated end-of-chapter questions in a variety of types that review each chapter’s concepts.

    • Contents

      Part I: An Introduction to Immunobiology and Innate Immunity
      Chapter 1: Basic Concepts in Immunology
      Chapter 2: Innate Immunity: The First Lines of Defense
      Chapter 3: The Induced Responses of Innate Immunity

      Part II: The Recognition of Antigen
      Chapter 4: Antigen Recognition by B-cell and T-cell Receptors
      Chapter 5: The Generation of Lymphocyte Antigen Receptors
      Chapter 6: Antigen Presentation to T Lymphocytes

      Part III: The Development of Mature Lymphocyte Receptor Repertoires
      Chapter 7: Lymphocyte Receptor Signaling
      Chapter 8: The Development and of B and T Lymphocytes

      Part IV: The Adaptive Immune Response
      Chapter 9: T Cell-Mediated Immunity
      Chapter 10: The Humoral Immune Response
      Chapter 11: Integrated Dynamics of Innate and Adaptive Immunity
      Chapter 12: The Mucosal Immune System

      Part V: The Immune System in Health and Disease
      Chapter 13: Failures of Host Defense Mechanisms
      Chapter 14: Allergy and Allergic Diseases
      Chapter 15: Autoimmunity and Transplantation
      Chapter 16: Manipulation of the Immune Response

    • Instructor Resources

      Instructor Resources

      Question Bank
      Question Bank written by Leslie Berg (University of Massachusetts Medical School) provides a comprehensive collection of questions that require the student to reflect upon and synthesize concepts in each chapter and can be used by instructors for the creation of exams.

      Animations and Videos
      There are over 40 narrated movies based on figures in the book and videos selected from visually compelling experiments.

      The Art of Immunobiology
      The figures and tables from the book are availableas individual JPEGs or preloaded into PowerPoint® presentations.

      Lecture Outlines
      The section headings, concept headings, and figures from the text have been integrated into PowerPoint presentations.

      The Garland Science Learning System
      The Garland Science Learning System is our new online homework platform designed to improve and track student performance. It allows instructors to select homework assignments on specific topics and review the performance of the entire class, as well as individual students, via the instructor dashboard. Janeway's Immunobiology will be available in late 2016.

      The user-friendly system provides a convenient way to gauge student progress, and tailor classroom discussion, activities, and lectures to areas that require specific remediation. The features and assignments include:

      Instructor Dashboard displays data on student performance, such as responses to individual questions and length of time spent to complete assignments.

      Tutorials explain essential or difficult concepts and are integrated with a variety of questions that assess student engagement and mastery of the material.


    • Student Resources

      Student Resources

      Animations and Videos

      Online Searchable Glossary

      Interactive Flashcards

    • E-Books and Custom Pub

      E-Books and Custom Pub

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      E-Books and Custom Publishing
      Garland Science Custom Publishing gives educators the ability to create their own course materials for use in the classroom-in e-book and/or print format. Faculty have complete control over what is added and may add chapters from Garland Science textbooks, web articles and blog postings, and self-authors content in PDF or Word format. Our site provides real-time copyright clearance, the ability to see a running total price as you build your book, and a cost savings for students.
      For more information visit

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