Skip Navigation

Book Search


Genetics and Genomics in Medicine

Edition:
1st
Author(s):
Tom Strachan, Judith Goodship, Patrick Chinnery
ISBN:
9780815344803
Format:
Paperback
Publication Date:
June 01, 2014
Content Details:
526 pages | 270 illustrations
Language:
English

Your Cart:

List Price:   $131.00

  
add to cart

Also of Interest

  • About the Book

    Book Summary

    Genetics and Genomics in Medicine is a new textbook written for undergraduate students, graduate students, and medical researchers that explains the science behind the uses of genetics and genomics in medicine today. Rather than focusing narrowly on rare inherited and chromosomal disorders, it is a comprehensive and integrated account of how genetics and genomics affect the whole spectrum of human health and disease. DNA technologies are explained, with emphasis on the modern techniques that have revolutionized the use of genetic information in medicine and are indicating the role of genetics in common diseases. Epigenetics and non-coding RNA are covered in-depth as are genetic approaches to treatment and prevention, including pharmacogenomics, genetic testing, and personalized medicine. Cancers are essentially genetic diseases and are given a dedicated chapter that includes new insights into its molecular basis and approaches to its detection gained from cancer genomics. Specific topics, including multiple examples of clinical disorders, molecular mechanisms, and technological advances, are profiled in boxes throughout the text. 

    Features

      Recent advances covered in the book include:

      • Mechanisms that explain how environmental factors contribute

      to disease by directly altering epigenetic settings.

      • Noninvasive prenatal testing (NIPT) and screening using

      massively parallel DNA sequencing.

      • The use of chromosome microarray technology and targeted

      genome sequencing in genetic testing.

      • Clinical and public health genomics.

  • Contents

    1. Fundamentals of DNA, Chromosomes, and Cells
    2. Fundamentals of Gene Structure, Gene Expression, and Human Genome Organization
    3. Principles Underlying Core DNA Technologies
    4. Principles of Genetic Variation
    5. Single-gene Disorders: Inheritance Patterns, Phenotype Variability, and Allele Frequencies
    6. Principles of Gene Regulation and Epigenetics
    7. Genetic Variation Producing Disease-Causing Abnormalities in DNA and Chromosomes
    8. Identifying Disease Genes and Genetic Susceptibility to Complex Disease
    9. Genetic Approaches to Treating Disease
    10. Cancer Genetics and Genomics
    11. Genetic Testing From Genes to Genomes, and the Ethics of Genetic Testing and Therapy

  • Instructor Resources

    Instructor Resources

    For the following resources, verified instructors can visit the resource page for Genetics and Genomics in Medicine.

    Figures from the book in PowerPoint and JPEG formats.

    Question Bank for qualified instructors.

  • Student Resources

    Student Resources

    End-of-Chapter questions, with answers available online.

    Additional questions and answers.

    Online Glossary and Flashcards.

  • E-Books and Custom Pub

    E-Books and Custom Publishing

    AMAZON KINDLE PRINT REPLICA
    Purchase in US ($) dollars
    Purchase in UK (£) pounds
    Purchase in Euros (€)

    VITALSOURCE
    Purchase or rent in US ($) dollars
    Purchase individual chapters in US ($) dollars
    Purchase or rent in UK (£) pounds

    CHEGG
    Purchase or rent in North America

    FOLLETT/BRYTEWAVE
    Purchase in North America

    GOOGLE PLAY
    Purchase in North America


    GARLAND SCIENCE CUSTOM PUBLISHING
    Garland Science Custom Publishing gives educators the ability to create their own course materials for use in the classroom-in e-book and/or print format. Faculty have complete control over what is added and may add chapters from Garland Science textbooks, web articles and blog postings, and self-authors content in PDF or Word format. Our site provides real-time copyright clearance, the ability to see a running total price as you build your book, and a cost savings for students.
    For more information visit http://www.garland.sharedbook.com.

  • Downloads