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Case Studies in Immunology

A Clinical Companion

Raif Geha, Luigi Notarangelo
Publication Date:
February 01, 2016
Content Details:
374 pages | 255 illustrations

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List Price:   $61.95

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  • About the Book

    Book Summary

    Case Studies in Immunology, Seventh Edition is intended for medical students and undergraduate and graduate students in immunology. It presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. Each case history is preceded by essential scientific facts about the immunological mechanisms of that specific disorder. The cases themselves demonstrate how immunological problems are deconstructed in the clinic and each one is followed by a concise summary of the clinical finding and questions which can serve as discussion points.

    The book includes a total of 55 cases and can be used as either a standalone text, review aid, or as a companion to Janeway’s Immunobiology, Ninth Edition and The Immune System, Fourth Edition.


      Key Features:
      -Concise presentation of basic scientific facts and clinical presentation and diagnosis of immunological disorders.
      -Cases are drawn from actual clinical practice and provide open-ended scenarios that leave room for thought and analysis.
      -Case study format presents the mechanisms underlying immunological dysfunction and aids in the diagnosis and treatment of immune disorders.
      -Discussion questions help students move beyond the stated facts to consider the implications of immunological disorders on other aspects of health and disease.
      -Can be used as both a stand-alone review aid or as a companion to Janeway’s Immunobiology, Ninth Edition, and The Immune System, Fourth Edition.
      -New topics to this edition include: Channelopathies, T-Cell Signaling Defects, LRBA Deficiency, PI3K Delta, Dock 8 Deficiency, and Increased Susceptibility to Candida Infections.

  • Contents

    1. X-linked Agammaglobulinemia 
    2. CD40 Ligand Deficiency 
    3. Activation-Induced Cytidine Deaminase Deficiency 
    4. Common Variable Immunodeficiency 
    5. X-linked Severe Combined Immunodeficiency 
    6. Adenosine Deaminase Deficiency 
    7. Omenn Syndrome 
    8. MHC Class II Deficiency 
    9. DiGeorge Syndrome 
    10. Acquired Immune Deficiency Syndrome (AIDS) 
    11. Graft-Versus-Host Disease
    12. MHC Class I Deficiency 
    13. X-linked Lymphoproliferative Syndrome 
    14. Hemophagocytic Lymphohistiocytosis 
    15. Chediak–Higashi Syndrome 
    16. Wiskott-Aldrich Syndrome
    17. Autoimmune Polyendocrinopathy–Candidiasis–Ectodermal Dystrophy (APECED) 
    18. Immune Dysregulation, Polyendocrinopathy, Enteropathy X-linked Disease 
    19. Autoimmune Lymphoproliferative Syndrome (ALPS) 
    20. Hyper IgE Syndrome
    21. Ataxia Telangiectasia 
    22. Warts, Hypogammaglobulinemia, Infections, and Myelokathexis Syndrome (WHIM Syndrome) 
    23. X-linked Hypohidrotic Ectodermal Dysplasia and Immunodeficiency 
    24. Interferon-γ Receptor Deficiency 
    25. Severe Congenital Neutropenia 
    26. Chronic Granulomatous Disease 
    27. Leukocyte Adhesion Deficiency 
    28. Recurrent Herpes Simplex Encephalitis 
    29. Interleukin 1 Receptor-Associated Kinase 4 Deficiency 
    30. Congenital Asplenia 
    31. Hereditary Angioedema 
    32. Deficiency of the C8 Complement Component
    33. Hereditary Periodic Fever Syndromes
    34. Systemic Juvenile Idiopathic Arthritis 
    35. Rheumatoid Arthritis 
    36. Systemic Lupus Erythematosus 
    37. Systemic Lupus Erythematosus 
    38. Multiple Sclerosis 
    39. Autoimmune Hemolytic Anemia 
    40. Myasthenia Gravis 
    41. Pemphigus Vulgaris 
    42. Celiac Disease 
    43. Acute Infectious Mononucleosis 
    44. Hemolytic Disease of the Newborn 
    45. Toxic Shock Syndrome 
    46. Lepromatous Leprosy 
    47. Allergic Asthma 
    48. Drug-induced Serum Sickness 
    49. Contact Sensitivity to Poison Ivy 
    50. Dedicator of Cytokinesis 8 Deficiency 
    51. Activated PI3KD Syndrome (APDS) 
    52. Increased Susceptibility to Candida Infections 
    53. LPS-Responsive Beige-Like Anchor (LRBA) Deficiency 
    54. T Cell Signaling Defects 
    55. Channelopathies

  • Instructor Resources

    Instructor Resources

    Art of Case Studies in Immunology
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