Skip Navigation

Book Search

< Back to Search Results

Case Studies in Cancer

A Clinical Companion to The Biology of Cancer

Edition:
1st
Author(s):
Richard Lee, Jeremy Abramson, Richard Goldsby
ISBN:
9780815345183
Format:
Paperback
Publication Date:
April 01, 2018
Content Details:
300 pages
Language:
English

Your Cart:

List Price:   $72.00

  
add to cart

Also of Interest

  • About the Book

    Book Summary

    The modern diagnosis and treatment of cancer is intricately tied to the molecular underpinnings of disease. Case Studies in Cancer highlights the broad range of malignancies in which known molecular pathways contribute to tumorigenesis, as well as susceptibility or resistance to therapy. Carefully selected case studies taken from the literature and practice of oncology explain specific examples of cancers and their management in the context of patient-centered case, which expose readers to the broad biological and clinical spectrum of cancer. Examined against the background of historical observations and concepts emerging from research in the molecular biology of cancer, these case studies provide a set of lessons showing how findings at the bench and bedside inform, direct, and inspire each other. Each case is accompanied by take-home points and review questions. Chapter summaries are followed by thought questions and primary and review literature for further reference on the history, biology, and clinical management of oncological disease. This text is appropriate for students starting medical school and those taking advanced courses in cancer biology with a clinical component, as well as practitioners in the field.

    Features

      • The modern diagnosis and treatment of cancer is intricately tied to the molecular underpinnings of disease. Case Studies in Cancer Biology highlights the broad range of malignancies in which known molecular pathways contribute to tumorigenesis, as well as susceptibility or resistance to therapy.
      • Authored by two practicing oncologists and an experienced instructor of immunology and cancer biology—this text teaches basic concepts in cancer biology in the context of real clinical experiences.
      • Each chapter begins with an introduction and epidemiology section, followed by diagnosis, work-up, and staging, segueing into case history, and ending with the management of localized and metastatic disease.
      • Topics bearing on Robert Weinberg’s The Biology of Cancer are highlighted throughout—Case Studies in Cancer Biology can be used as a clinical companion or as a stand-alone text.
      • Richly illustrated, the text provides key take-home points, thought questions, and important references bearing on the cases for further study.
  • Contents

    1. Overview of Cancer and Clinical Oncology

    2. Introduction to Cancer Therapy

    3. Cytotoxic Chemotherapy

    4. Protein Kinase Inhibition

    5. Inhibition of the PI3-Kinase/Akt/mTOR Pathway

    6. Hormone Therapy

    7. Differentiation Therapy

    8. Epigenetic Therapy

    9. Targeting Protein Degradation and DNA Repair

    10. Interference with the Tumor Microenvironment

    11. Immunological Strategies: Monoclonal Antibodies

    12. Immunological Strategies – Vaccination and Adoptive T-Cell Transfer