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Neuroprosthetics

Principles and Applications

Edition:
1st
Author(s):
Justin C. Sanchez
ISBN:
9781138749443
Format:
Paperback
Publication Date:
July 26, 2017
Content Details:
236 pages
Language:
English

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List Price:   $64.95

  
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Hardback
$130.00

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  • About the Book

    Book Summary

    Master the tools of design thinking using Neuroprosthetics: Principles and Applications. Developed from successfully tested material used in an undergraduate and graduate level course taught to biomedical engineering and neuroscience students, this book focuses on the use of direct neural sensing and stimulation as a therapeutic intervention for complex disorders of the brain. It covers the theory and applications behind neuroprosthetics and explores how neuroprosthetic design thinking can enhance value for users of a direct neural interface.

    The book explains the fundamentals of design thinking, introduces essential concepts from neuroscience and engineering illustrating the major components of neuroprosthetics, and presents practical applications. In addition to describing the approach of design thinking (based on facts about the user’s needs, desires, habits, attitudes, and experiences with neuroprosthetics), it also examines how effectively "human centered" neuroprosthetics can address people’s needs and interactions in their daily lives.

    Identifying concepts and features of devices that work well with users of a direct neural interface, this book:

    • Outlines the signal sensing capabilities and trade-offs for common electrode designs, and determines the most appropriate electrode for any neuroprosthetic application
    • Specifies neurosurgical techniques and how electronics should be tailored to capture neural signals
    • Provides an understanding of  the mechanisms of neural–electrode performance and information contained in neural signals
    • Provides understanding of neural decoding in neuroprosthetic applications
    • Describes the strategies that can be used to promote long-term therapeutic interventions for humans through the use of neuroprosthetics

    The first true primary text for undergraduate and graduate students in departments of neuroscience and bioengineering that covers the theory and applications behind this science, Neuroprosthetics: Principles and Applications provides the fundamental knowledge needed to understand how electrodes translate neural activity into signals that are useable by machines and enables readers to master the tools of design thinking and apply them to any neuroprosthetic application.

    Features

      • Covers the latest state-of-the-art theory and applications of neural devices and implants
      • Contains numerous end-of-chapter problems and examples
      • Includes extensive references to enhance additional study
  • Contents

    Design Thinking for Neuroprosthetics
    Learning Objectives
    Introduction
    Design Thinking
    Inspiration for Neuroprosthetic Design
    Prototypical Example of Neuroprosthetic Design Thinking
    Exercise

    Interfaces to the Brain
    Learning Objectives
    Introduction
    Electrical Interfaces
    Electrode Design
    Exercises

    Electronics for Recording
    Learning Objectives
    Introduction
    Use of Sensors
    What Is a Signal?
    What Is Noise?
    Biopotential Amplifiers
    Filtering
    Adaptive Filters
    Conclusion
    Exercises

    Surgical Techniques for Implantation and Explanation of Microelectrode Arrays
    Learning Objectives
    Introduction
    Targeting
    Surgical Methods for Implantation
    Surgical Methods for Perfusion
    Surgical Methods for Explanation
    Exercises

    Quantifying Long-Term Electrode Performance
    Learning Objectives
    Introduction
    Morphological Properties
    Electrical Properties
    Tissue Properties
    Holistic Abiotic and Biotic Analysis
    Conclusion
    Exercises

    Neural Decoding
    Learning Objectives
    Introduction
    Evolution of Decoders
    Extracting Neural Features as Control Signals
    Examples of Neuroprosthetic Decoders
    Exercises

    Principles of Stimulation
    Learning Objectives
    Introduction
    Nerve Responses to Electrical Current
    Strength–Duration Curves
    Current Flow
    Current Types
    Example Applications
    Exercises

    Application: Brain-Actuated Functional Electrical Stimulation for Rehabilitation
    Learning Objectives
    Introduction
    Hand Rehabilitation Strategies
    Fundamentals of Functional Electrical Stimulation
    Functional Outcome Measures
    An Exemplar of Closed-Loop Neuroprosthetic Control of FES
    Closed-Loop Trials
    Conclusion
    Exercises

    Design of Implantable Neural Interface Systems
    Learning Objectives
    Introduction
    Design
    Safety
    Exercises

    Application: Deep Brain Stimulation for Neuropsychiatric Disorders
    Learning Objectives
    Introduction
    DBS as a Foundational Technology
    Shifts in Research/Practice Paradigms
    Second-Generation Experimental Paradigms—Application of DBS for Tourette Syndrome
    Conclusion
    Exercise

    References