Skip Navigation

Book Search

< Back to Search Results

Virulence Mechanisms of Bacterial Pathogens

Publication Date:
April 25, 2000
Content Details:
312 pages

Your Cart:

List Price:   Sorry, not available in your region


Also of Interest

  • About the Book

    Book Summary

    The field of microbial pathogenesis has expanded rapidly over the past decade. Literally thousands of research papers have been published and new specialty journals on microbial pathogenesis have appeared, giving rise to the need for a text that reviews the entire field of bacterial virulence mechanisms and summarizes the major advances. The third edition of this best-selling volume provides an overview of current knowledge of the wide variety of mechanisms used by bacterial pathogens in establishing infection, producing disease, and persisting in the host. Internationally recognized authorities in the field review bacterial invasion, colonization, and survival; bacterial evasion of host defense mechanisms; bacterial effects on host cell function; and identification, regulation, and transfer of virulence genes. The final chapter presents an interesting examination of new methods for studying virulence mechanisms in the complex in vivo environment, a major development in studies of bacterial pathogenicity. The overall emphasis is on understanding the mechanisms of host-pathogen interactions rather than on focusing on specific research approaches. Virulence Mechanisms of Bacterial Pathogens, 3rd Edition is valuable reading for molecular biologists, infectious disease specialists, researchers, industry scientists, faculty, and graduate students.
  • Contents

    Table of Contents Organizing Committee Contributors Preface Acknowledgments I. Bacterial Invasion, Colonization, and Survival Section Editors: James A. Roth and Thad B. Stanton 1. Bacterial Adherence, Colonization, and Invasion of Mucosal Surfaces, John H. Brumell and B. Brett Finlay 2. Bacterial Evasion of Host-Derived Antimicrobial Peptides on Mucosal Surfaces, Kim Alan Brogden 3. Consequences of Bacterial Invasion into Nonprofessional Phagocytic Cells, Jeffrey B. Lyczak and Gerald B. Pier 4. Ecological Aspects of Host Colonization: Coaggregation, Osmoadaptation, and Acid Tolerance or Resistance, Thaddeus B. Stanton 5. Relationships between Community Behavior and Pathogenesis in Pseudomonas aeruginosa, Matthew R. Parsek and E.P. Greenberg 6. Antibiotic Resistance and Survival in the Host, Emma L.A. Macfarlane and Robert E.W. Hancock II. Bacterial Evasion of Host Defense Mechanisms Section Editor: Carole A. Bolin 7. What Is the Very Model of a Modern Macrophage Pathogen? David G. Russell 8. Bacterial Resistance to Antibody-Dependent Defenses, Lynette B. Corbeil 9. Mechanisms of Resistance to NO-Related Antibacterial Activity, Andres Vazquez-Torres and Ferric C. Fang 10. DNA Repair and Mutators: Effects on Antigenic Variation and Virulence of Bacterial Pathogens, Thomas A. Cebula and J. Eugene LeClerc III. Bacterial Effects on Host Cell Function Section Editor: Michael J. Wannemuehler 11. Bacterial Toxins in Disease Production, Joseph T. Barbieri and Kristin J. Pederson 12. Exploitation of Mammalian Host Cell Function by Shigella spp., Larean D. Brandon and Maricia B. Goldberg 13. Bacterial Induction of Cytokine Secretion in Pathogenesis of Airway Inflammation, Alice Prince 14. The Type III Secretion Pathway: Dictating the Outcome of Bacterial-Host Interactions, Raymond Schuch and Anthony T. Maurelli IV. Identification, Regulation, and Transfer of Virulence Genes Section Editor: F. Chris Minion 15. Impact of Horizontal Gene Transfer on Evolution of Salmonella Pathogenesis, Robert A. Kingsley, Renee M. Tsolis, Stacy M. Townsend, Tracy L. Norris, Thomas A. Ficht, L. Garry Adams, and Andreas J. Baumler 16. Regulation of Virulence Gene Expression In Vivo, James M. Slauch 17. Identification of Virulence Genes in Silico: Infectious Disease Genomics, George M. Weinstock, Steven J. Norris, Erica J. Sodergren, and David Smajs V. Concluding Perspective Section Editor: Kim A. Brogden 18. State and Future of Studies on Bacterial Pathogenicity: Impact of New Methods of Studying Bacterial Behavior In Vivo, H. Smith