Magic Bullets To Conquer Malaria
from Quinine to Qinghaosu
- Irwin W Sherman
- Publication Date:
- November 16, 2010
- Content Details:
- 312 pages
Also of Interest
A clear, concise discourse of 300 years of malarial drug research. • Presents a historical overview of antimalarial medicines and examines future challenges in the discovery and development of effective treatments and control strategies. • Provides new perspectives on the creative process of drug discovery and the challenges of overcoming drug resistance. • Discusses the use of larvicides, bednets, and DDT as well as recombinant DNA and monoclonal antibodies to block malaria transmission from mosquitoes to humans. • Serves as a resource for microbiologists, parasitologists, pharmacologists, medicinal chemists, biochemists, physicians, and drug researchers.
This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.
Table of Contents 1. From Breathing Bad Air to Biting Beasts 2. Myth to Medicine: Quinine 3. Synthetic Dyes to Drugs: Atabrine and Chloroquine 4. Antimicrobials to Antimalarials: Prontosil, Pyrimethamine, Proguanil, and Atovaquone 5. To Destroy Liver Stages: Primaquine and Tafenoquine 6. Quinine to Mefloquine 7. Reversal of Fortune 8. Sweet Wormwood of Success: Qinghaosu 9. Antibiotics and the Apicoplast 10. A Possible Dream: Control by Blocking Transmission 11. The Dream of Eradication 12. A Reasonable Dream