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Molecular Genetics of Mycobacteria

Edition:
2nd
Author(s):
Graham Hatful, William Jacobs Jr.
ISBN:
9781555818838
Format:
Hardback
Publication Date:
October 09, 2014
Content Details:
824 pages
Language:
English

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  • About the Book

    Book Summary

    Molecular Genetics of Mycobacteria is a comprehensive collection of perspectives written by leading experts in the field. Molecular Genetics of Mycobacteria covers the key areas of current research in mycobacterial genetics, including genomics and genetic exchange, gene expression and regulation, proteomics, metabolism, biosynthesis, and drug sensitivities of M. tuberculosis, and presents genetic approaches for manipulating M. tuberculosis. This book is an invaluable resource for anyone interested in the molecular genetics and biology of mycobacteria.

    This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.

  • Contents

    GENOMES, GENOMICS, AND GENETIC EXCHANGE
    1. Gene Transfer in Mycobacterium tuberculosis: Shuttle Phasmids to Enlightenment, William R. Jacobs, Jr.
    2. Mycobacterial Pathogenomics and Evolution, Daria Bottai, Timothy P. Stinear, Philip Supply, and Roland Brosch
    3. BCG Vaccines, Vanessa Tran, Jun Liu, and Marcel A. Behr
    4. Distributive Conjugal Transfer: New Insights into Horizontal Gene Transfer and Genetic Exchange in Mycobacteria, Keith M. Derbyshire and Todd A. Gray
    5. Molecular Genetics of Mycobacteriophages, Graham F. Hatfull
    6. Genetics of Phage Lysis, Madalena Pimentel

    GENE EXPRESSION AND REGULATION
    7. Sigma Factors: Key Molecules in Mycobacterium tuberculosis Physiology and Virulence, Riccardo Manganelli
    8. Transcription Factor Binding Site Mapping Using ChIP-Seq, Suma Jaini, Anna Lyubetskaya, Antonio Gomes, Matthew Peterson, Sang Tae Park, Sahadevan Raman, Gary Schoolnik, and James Galagan
    9. Noncoding RNA in Mycobacteria, Kristine B. Arnvig, Teresa Cortes, and Douglas B. Young
    10.Two-Component Regulatory Systems of Mycobacteria, Tanya Parish
    11.Regulated Expression Systems for Mycobacteria and Their Applications, Dirk Schnappinger and Sabine Ehrt

    THE MYCOBACTERIAL PROTEOME
    12.Mycobacterium tuberculosis in the Proteomics Era, Martin Gengenbacher, Jeppe Mouritsen, Olga T. Schubert, Ruedi Aebersold, and Stefan H. E. Kaufmann
    13.Structural Annotation of the Mycobacterium tuberculosis Proteome, Nagasuma Chandra, Sandhya Sankaran, and Praveen Anand
    14.Cyclic AMP Signaling in Mycobacteria, Gwendowlyn S. Knapp and Kathleen A. McDonough

    METABOLISM
    15.The Physiology and Genetics of Oxidative Stress in Mycobacteria, Bridgette M. Cumming, Dirk Lamprecht, Ryan M. Wells, Vikram Saini, James H. Mazorodze, and Adrie J. C. Steyn
    16.Metabolomics of Central Carbon Metabolism in Mycobacterium tuberculosis, Anthony D. Baughn and Kyu Y. Rhee
    17.Mycobacterial Lipidomics, Emilie Layre, Reem Al-Mubarak, John T. Belisle, and D. Branch Moody
    18.Genetics of Mycobacterial Trehalose Metabolism, Rainer Kalscheuer and Hendrik Koliwer-Brandl
    19.Metallobiology of Tuberculosis, G. Marcela Rodriguez and Olivier Neyrolles
    20.Energetics of Respiration and Oxidative Phosphorylation in Mycobacteria, Gregory M. Cook, Kiel Hards, Catherine Vilchèze, Travis Hartman, and Michael Berney

    GENETICS OF DRUG RESISTANCE
    21.Molecular Basis of Drug Resistance in Mycobacterium tuberculosis, Keira A. Cohen, William R. Bishai, and Alexander S. Pym
    22.Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis: Genes, Mutations, and Causalities, Catherine Vilchèze and William R. Jacobs, Jr.
    23.The Molecular Genetics of Fluoroquinolone Resistance in Mycobacterium tuberculosis, Claudine Mayer and Howard Takiff
    24.Mechanisms of Pyrazinamide Action and Resistance, Ying Zhang, Wanliang Shi, Wenhong Zhang, and Denis Mitchison
    25.Genetic Strategies for Identifying New Drug Targets, Andrej Trauner, Christopher M. Sassetti, and Eric J. Rubin

    GENETICS OF MEMBRANE AND CELL WALL BIOSYNTHESIS
    26.Genetics of Peptidoglycan Biosynthesis, Martin S. Pavelka, Jr., Sebabrata Mahapatra, and Dean C. Crick
    27.Genetics of Mycobacterial Arabinogalactan and Lipoarabinomannan Assembly, Monika Jankute, Shipra Grover, Helen L. Birch, and Gurdyal S. Besra
    28.Genetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids, Mamadou Daffé, Dean C. Crick, and Mary Jackson
    29.The Molecular Genetics of Mycolic Acid Biosynthesis, Jakub Pawełczyk and Laurent Kremer

    GENETICS OF MACROMOLECULAR BIOSYNTHESIS
    30.Nucleotide Metabolism and DNA Replication, Digby F. Warner, Joanna C. Evans, and Valerie Mizrahi
    31.Double-Strand DNA Break Repair in Mycobacteria, Michael S. Glickman
    32.The Pup-Proteasome System of Mycobacteria, Nadine J. Bode and K. Heran Darwin
    33.Mycobacterium tuberculosis Serine/Threonine Protein Kinases, Sladjana Prisic and Robert N. Husson

    THE MYCOBACTERIAL LIFESTYLE, PERSISTENCE, AND MACROPHAGE SURVIVAL
    34.The Spectrum of Drug Susceptibility in Mycobacteria, Bree B. Aldridge, Iris Keren, and Sarah M. Fortune
    35.The Sculpting of the Mycobacterium tuberculosis Genome by Host Cell-Derived Pressures, David G. Russell, Wonsik Lee, Shumin Tan, Neelima Sukumar, Maria Podinovskaia, Ruth J. Fahey, and Brian C. VanderVen
    36.Evasion of Innate and Adaptive Immunity by Mycobacterium tuberculosis, Michael F. Goldberg, Neeraj K. Saini, and Steven A. Porcelli
    37.Mycobacterial Biofilms, Jacobs P. Richards and Anil K. Ojha