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Dictyostelium Genomics

Edition:
1st
Author(s):
William F. Loomis, Adam Kuspa
ISBN:
9781904933137
Format:
Hardback
Publication Date:
June 15, 2005
Content Details:
400 pages | 5 illustrations
Language:
English

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List Price:   $344.00

  
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  • About the Book

    Book Summary

    Dictyostelium discoideum is a model eukaryotic organism for basic biomedical research in cell and developmental biology and for the functional analysis of sequenced genes. The organism has unique advantages for studying fundamental cellular processes such as cytokinesis, motility, phagocytosis, chemotaxis, signal transduction, cell sorting, pattern formation, and cell-type determination.

    This book, written to coincide with the publication of the genome sequence of Dictyostelium, introduces the post-genomic era and focuses on the important aspects of Dictyostelium genomics. Leading experts in the field have contributed chapters on genomic mapping and sequencing, databases, multigene families, regulation of gene expression, signal transduction, the microfilament system, the GTPase superfamily, the kinome, glycosyltransferase genomics, and whole-genome functional analysis.

    Reviews

      This is a gold mine of information for those interested in genomics research. A major strength of this book is that it provides up-to-date information, based on solid interpretation of the genome sequence... The book is clearly written, carefully edited, and east to read - B. A. Fenderson, Thomas Jefferson University, USA, Doody'e Book Review Service
  • Contents

    1. Mapping and Sequencing the Dictyostelium Genome. 2. dictyBase: Using the Genome to Organize Dictyostelium Biology. 3. Metabolic Pathways. 4. Multigene Families of Dictyostelium. 5. Components of the Dictyostelium Gene Expression Regulatory Machinery. 6. Signal Transduction via G-Protein-Coupled Receptors, Trimeric G Proteins, and RGS Proteins. 7. The Microfilament System of Dictyostelium discoideum. 8. The Small GTPase Superfamily. 9. The Dictyostelium Kinome and Protein Kinase Pathways that Regulate Growth and Development. 10. Glycosyltransferase Genomics in Dictyostelium discoideum. 11. How Many Protein Encoding Genes Does Dictyostelium discoideum Have? 12. Whole-Genome Functional Analyses in Dictyostelium.